Replicating
human tissue
at scale
Replicating
human tissue
at scale
Until this day there is no solution to replicate human tissue and organs at scale.
Transplantation medicine and plastic surgery rely on artificial materials without physiologic functionality or transplants from human and animal sources that require immunosuppression.
Cellbricks vision is a future where biofabrication of organs and
human tissue is common medical practice so humans can enjoy longer and healthier lives.
Cartilage
2.6m patients p.a.
2.3m patients p.a.
30% of western population affected by NAFLD
420m diabetes patients
2m patients
Human tissue is complex -
so is the challenge to biofabricate it
The building blocks of life consist of highly specialized cells and a complex extracellular matrix…
… organized in highly structured micro-units…
… that together, perform the vital functions of a living organism.
4 conflicting
key requirements
high
resolution
multiple cell types
& materials
human like
extracellular matrix
large volumes
and high speed
Cellbricks combines Synthetic Biology & 3D-Bioprinting to replicate human tissue
Bioinks
We develop our own
application-tailored bioinks via synthetic biology and chemical engineering.
Tissue Engineering
We leverage world
leading know-how in tissue engineering, with a track record of stereolithographic
bioprinting various vital mini-organs with multiple materials and cell types.
3D Bioprinting
We invented multi- material
stereolitho-graphic bioprinting and own the complete tech stack of proprietary hardware,
software and process engineering.
Cellbricks’ patented* multi-material bio-printing Technology combines speed, precision and scalability
Tailor made Bioinks - the implantable ECM
Cellbricks converts a digital, high resolution model of the tissue into a stack of slices for each material to be printed.
A high resolution UV projector projects the slice image onto the surface of the print, immersed in bio-ink. The bio-ink solidifies into a thin layer of ECM with embedded cells.
The print is dipped into the next bio-ink to add a second material as specified by the corresponding slice image. More materials can be added after the same method.
In the finished print, multiple cell types and matrices are arranged in a complex 3D structure, added layer by layer.
We master tissue engineering and our end-to-end biofabrication technology
in cooperation with Charité
Lam et al.
functional liver
Lam et al.
in cooperation with Charité & JWI
Thomas et al.
in cooperation with BfR
in revision
disease model for drug development
Grunewald et al.
functional placenta barrier
Kreuder et al.
Cellbricks is a highly interdisciplinary team
Our fast growing team is made up of 20 biotech enthusiasts, scientists, PhDs, engineers, chemists and entrepreneurs from excellent universities and top companies from all over the world. Through long-standing cooperations we work together closely with KOLs in science, medicine and pharma.
Dr. Lutz Kloke, Founder & CSO
Alexander Leutner, MD
Joachim von Arnim, MD
Contact
Do you want to get in touch?
Contact the teamCareer Opportunities at Cellbricks
Bring the future of bio-fabrication to live with us. Join the team!
Covering the entire
process chain of bio-fabrication, including synthetic biology, printer technology, 3D cell
culture as well as tissue engineering, Cellbricks offers plenty of exciting opportunities.
We are always looking for new, motivated members of the team:
This isn’t you? No problem. Tell us who you are, what your motivation is and how you want to contribute to fulfill Cellbricks' ambitious goals.
Click here to send your application, including CV and references.
Equal Opportunity Statement
We are an equal-opportunity employer and value diversity. We consider all applications equally regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity. Furthermore, we strongly encourage individuals from groups traditionally underrepresented in tech to apply.